| Raw Material | Isotretinoin |
|---|---|
| Water Retention | No |
| Hepatotoxicity | Moderate, requires periodic liver function tests |
| Lab Test | Liver function tests, lipid profiles, pregnancy tests |
| Also known as | 13-cis-Retinoic acid |
| Blood pressure | No significant effect |
| Trade name | Accutane, Roaccutane, Claravis, others |
| Storage conditions | Store at controlled room temperature (15-30В°C), protect from light |
| Chemical name | (2Z, 4E, 6E, 8E)-3, 7-dimethyl-9-(2, 6, 6-trimethylcyclohexen-1-yl)nona-2, 4, 6, 8-tetraenoic acid |
| Formula | C20H28O2 |
| Substance class | Retinoid |
| Main action | Reduces sebum production, corrects abnormal keratinization, has anti-inflammatory properties |
| Half-life | 10-20 hours |
| Dosage (medical) | Typically 0.5 to 1 mg per kg of body weight per day, taken in two divided doses |
| Dosage (sports) | Not applicable |
| Effects | Reduces acne, decreases sebum production, promotes skin renewal |
| Side effects | Dry skin, lips and eyes, itching, nosebleeds, muscle aches, sensitivity to sunlight, decreased night vision, potentially severe birth defects if taken during pregnancy |
| Use in sports | None |
| Manufacturer | ROCHE TR |
| Packing | 30 caps x 20 mg |
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